Journal: ACS Chemical Neuroscience

Article Title: Neurotropic activity and safety of methylene-cycloalkylacetate (MCA) derivative 3-(3-allyl-2-methylenecyclohexyl) propanoic acid

doi: 10.1021/acschemneuro.0c00255

Figure Lengend Snippet: HU- MCA-13 induced neurotropic effect in different neuronal cultures. Neurotropic effect was measured after treatment with 5 μM of HU-MCA-13 of rat PC12 dopaminergic neurons (7 days, top row), mice dorsal root ganglion (DRG) explants (5 days, middle row) and rat spinal cord sensory neurons (14 days, bottom row). The negative control cultures were treated with 0.1% DMSO and the positive control cultures were treated with 50 ng/mL mouse β-nerve growth factor (NGF) for the same periods of time.

Article Snippet: Tissue culture grade mouse β-NGF, was purchased from Alomone Laboratories (Jerusalem, Israel).

Techniques: Negative Control, Positive Control

Journal: Human Brain Mapping

Article Title: A novel concurrent TMS‐fMRI method to reveal propagation patterns of prefrontal magnetic brain stimulation

doi: 10.1002/hbm.24307

Figure Lengend Snippet: (a) Location of facial markers and TMS targets in the neural navigator. The statistical map of voluntarily‐induced motor activity is thresholded and shown in red. Facial markers: Tip of the nose; nasion, left and right inner eyelid; left and right upper and lower ear. TMS targets: Primary motor cortex (M1); dorsolateral prefrontal cortex (DLPFC). (b) TMS coil probes. The probes are visualized in a T2‐weighted scan to determine their location with respect to the head. (c) Participant is lying on the MR bed with the head positioned in between two MR receive coils and the TMS coil located over the cranium [Color figure can be viewed at http://wileyonlinelibrary.com ]

Article Snippet: Both experiments were done using a biphasic Magstim Rapid 2 magnetic stimulator, an MR‐compatible TMS coil and a custom designed TMS filter box (all manufactured by Magstim Inc., Whitland, The United Kingdom, http://www.magstim.com ; De Weijer et al., ; Mandija, Petrov, Neggers, Luijten, & Berg, ).

Techniques: Activity Assay

Journal: Human Brain Mapping

Article Title: A novel concurrent TMS‐fMRI method to reveal propagation patterns of prefrontal magnetic brain stimulation

doi: 10.1002/hbm.24307

Figure Lengend Snippet: (a) Activity in the primary motor cortex in response to voluntary thumb movements (in red) and the location of the TMS coil isocenter during the TMS‐fMRI session is shown (in blue). (b) Activity in response to voluntary thumb movements contrasted with baseline activity ( p < .05, FWE corrected). Axial slices of an MNI brain are shown (left = left). (c) TMS‐induced activity in response to TMS pulses of 115% RMT contrasted with baseline activity ( p < .05, FWE corrected). The same slices are shown as in (b) [Color figure can be viewed at http://wileyonlinelibrary.com ]

Article Snippet: Both experiments were done using a biphasic Magstim Rapid 2 magnetic stimulator, an MR‐compatible TMS coil and a custom designed TMS filter box (all manufactured by Magstim Inc., Whitland, The United Kingdom, http://www.magstim.com ; De Weijer et al., ; Mandija, Petrov, Neggers, Luijten, & Berg, ).

Techniques: Activity Assay

Journal: Human Brain Mapping

Article Title: A novel concurrent TMS‐fMRI method to reveal propagation patterns of prefrontal magnetic brain stimulation

doi: 10.1002/hbm.24307

Figure Lengend Snippet: (a) TMS targets projected onto individual brain surfaces. The numbers refer to the participant numbers in Table . The red dot indicates the location of the hand area in the primary motor cortex (M1) as determined through fMRI. (b) The normalized COG of each individual TMS target projected onto an MNI brain. The TMS targets are based on initial TMS coil placement (as determined through a T2‐weighted scan) and corrected for subsequent head movement during image acquisition (as determined through realignment of the EPI volumes). Corresponding colors are used in (a) and (b) and Table [Color figure can be viewed at http://wileyonlinelibrary.com ]

Article Snippet: Both experiments were done using a biphasic Magstim Rapid 2 magnetic stimulator, an MR‐compatible TMS coil and a custom designed TMS filter box (all manufactured by Magstim Inc., Whitland, The United Kingdom, http://www.magstim.com ; De Weijer et al., ; Mandija, Petrov, Neggers, Luijten, & Berg, ).

Techniques:

Journal: Human Brain Mapping

Article Title: A novel concurrent TMS‐fMRI method to reveal propagation patterns of prefrontal magnetic brain stimulation

doi: 10.1002/hbm.24307

Figure Lengend Snippet: TMS‐induced activity in response to TMS pulses of 115% RMT contrasted with TMS pulses of 60% RMT ( p < .05, FWE corrected). Axial slices of an MNI brain are shown (left = left). (a)–(i) show TMS‐induced activity of Participants 1, 2, and 4–10 [Color figure can be viewed at http://wileyonlinelibrary.com ]

Article Snippet: Both experiments were done using a biphasic Magstim Rapid 2 magnetic stimulator, an MR‐compatible TMS coil and a custom designed TMS filter box (all manufactured by Magstim Inc., Whitland, The United Kingdom, http://www.magstim.com ; De Weijer et al., ; Mandija, Petrov, Neggers, Luijten, & Berg, ).

Techniques: Activity Assay

Journal: Human Brain Mapping

Article Title: A novel concurrent TMS‐fMRI method to reveal propagation patterns of prefrontal magnetic brain stimulation

doi: 10.1002/hbm.24307

Figure Lengend Snippet: TMS‐induced activity in response to TMS pulses of 115% RMT contrasted with TMS pulses of 60% RMT ( p < .05, FWE corrected). Axial slices of an MNI brain are shown (left = left). (a) and (b) show TMS‐induced activity in two different participants in which the TMS target was very similar. Left is left. (a) TMS‐induced activity of Participant 9. (b) TMS‐induced activity of Participant 10 [Color figure can be viewed at http://wileyonlinelibrary.com ]

Article Snippet: Both experiments were done using a biphasic Magstim Rapid 2 magnetic stimulator, an MR‐compatible TMS coil and a custom designed TMS filter box (all manufactured by Magstim Inc., Whitland, The United Kingdom, http://www.magstim.com ; De Weijer et al., ; Mandija, Petrov, Neggers, Luijten, & Berg, ).

Techniques: Activity Assay

Journal: Human Brain Mapping

Article Title: A novel concurrent TMS‐fMRI method to reveal propagation patterns of prefrontal magnetic brain stimulation

doi: 10.1002/hbm.24307

Figure Lengend Snippet: TMS‐induced activity in response to TMS pulses of 115% RMT contrasted with TMS pulses of 60% RMT ( p < .05, FWE corrected). Sagittal slices of an MNI brain are shown (first slice = left side; last slice = right side). (a) TMS‐induced activity of Participant 5. (b) TMS‐induced activity of Participant 7. (c) TMS‐induced activity of Participant 8. (d) TMS‐induced activity of Participant 9 [Color figure can be viewed at http://wileyonlinelibrary.com ]

Article Snippet: Both experiments were done using a biphasic Magstim Rapid 2 magnetic stimulator, an MR‐compatible TMS coil and a custom designed TMS filter box (all manufactured by Magstim Inc., Whitland, The United Kingdom, http://www.magstim.com ; De Weijer et al., ; Mandija, Petrov, Neggers, Luijten, & Berg, ).

Techniques: Activity Assay